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Tatiana K. Bronich Ph.D


Tatiana K. Bronich, Ph.D

Professor
Center for Drug Delivery and Nanomedicine and
Department of Pharmaceutical Sciences
College of Pharmacy

Campus address:
Durham Research Center, Room # 1041
985830 Nebraska Medical Center
Omaha, NE 68198-5830
Tel. (402) 559-9351
Fax: (402) 559-9365
E-mail: tbronich@unmc.edu

                    
Teaching activities:
At the professional level Dr. Bronich lectures in Applied Biochemistry course where she utilizes her expertise in the area of gene therapy. At the graduate level Dr. Bronich is a co-coordinator and lecturer for the Polymer Therapeutics course. In addition, Dr. Bronich lectures on light scattering techniques in Quantitative Pharmaceutical Analysis course and coordinates the Physical Section of Current Topics in Pharmaceutical Sciences.
Research Activities/Interests:
Dr. Bronich's research interests are in the area of self-assembling polymer materials and applications of these materials in medicine. Of special interest is the design and study of novel types of functional materials based on complexes formed between block ionomers and oppositely charged polymers and low molecular weight amphiphilic molecules. These systems are of great fundamental importance as models of biological systems formed as a result of self-assembly processes. In addition, her recent work has expanded to include the application of these amphiphilic block copolymers and block ionomer complexes in drug delivery to treat cancer and the development of the polycation-DNA complexes for gene delivery.

Recent Publications:
1. Solomatin, S.V., Bronich, T.K., Bargar, T.W., Kabanov, V.A., Eisenberg, A., Kabanov, A.V. Environmentally responsive nanoparticles from block ionomer complexes: Effects of pH and ionic strength. Langmuir, 19: 8069-8076, 2003.
2. Bronich, T.K., Ouyang, M., Eisenberg, A., Kabanov, V.A., Szoka, F.C., Kabanov, A.V. Synthesis of vesicles on polymer template. J. Am. Chem. Soc., 124: 11872-11873, 2002.
3. Bronich, T., Kabanov, A.V., Marky, L.A. A thermodynamic characterization of the interaction of a cationic copolymer with DNA. J. Phys. Chem. B. 105:6042-6050, 2001.
4. Bronich, T.K., Vinogradov, S.V., Kabanov, A.V. Interaction of nanosized copolymer networks with oppositely charged amphiphilic molecules. Nano Letters. 1(10):535-540, 2001.
5. Bronich, T.K., Nguyen H.-K., Eisenberg A., Kabanov, A.V. Recognition of DNA topology in reactions between plasmid DNA and cationic copolymers. J. Am. Chem. Soc. 120: 9941-9942, 2000.