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Srikanth Sriadibhatla

Graduate Student

College of Pharmacy

Durham Research Center

First Floor, Room No: 1030

985830 Nebraska Medical Center

Omaha, NE 68198-5830

Tel. (402) 559-5256

e-mail: ssriadi@unmc.edu

 

Research interests

Formulation, Optimization and Effect of Pluronic Block Copolymers on Gene Expression in vitro and in vivo

 

Education

2001 - Present    Ph.D. Student Pharmaceutical Sciences Department, UNMC, Omaha, NE

1999 - 2000        M.Pharm. University college of Pharmaceutical Sciences, Warangal, India

1995 - 1999        B.Pharm., University college of Pharmaceutical Sciences, Warangal, India

 

Awards/Accomplishments

§         AAPS-2005 Graduate Symposium Award in Biotechnology, sponsored by The Pfizer Global Biologics for excellence in graduate research

§          Travel Scholarship from Third International Nanomedicine and Drug Delivery Symposium’05

§          Best Podium Presentation (2005) at the Annual PSGP Meeting

§          Recipient of UNMC fellowship for graduate studies (2003-2005)

§          Recipient of Junior Research Fellowship (JRF) from University Grants Commission (UGC), India (Mar’98 – Mar’00)

 

Publications

§          Sriadibhatla, S., Yang, Z., Gebhart, C.L., Alakhov, V.Y and Kabanov, A.V. Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells. Mol Ther. 2005 Sep 29; [Epub ahead of print]

§          Yang, Z., Zhu, J., Sriadibhatla, S., Gebhart, C.L., Alakhov, V.Y and Kabanov, A.V. Promoter- and strain- selective enhancement of gene expression in a mouse skeletal muscle by a polymer excipient Pluronic P85. Journal of Controlled Release 108(2-3), 496-512 (2005)

§          Kabanov, A.V., Sriadibhatla, S and Alakhov, V.Y. Pluronic® Block Copolymers for Gene Delivery in Mansoor. M. Amiji (Ed.), Polymeric Gene Delivery: Principles and Applications, CRC Press, pp.313-328 (2005)

§          Kabanov, A.V, Batrakova, E.V., Sriadibhatla, S., Yang, Z., Kelly, D.L., and Alakhov, V. Polymer genomics: shifting the gene and drug delivery paradigms. Journal of Controlled Release 101(5), 259-271 (2005)

§          Kabanov, A.V., Sriadibhatla, S., Gebhart, C.L., Yang, Z and Alakhov, V.Y. Effect of Pluronic Block Copolymers on Gene Expression. Polymer Prepr (Am. Chem. Soc., Div. Polym. Chem) 45 (2), 392-393 (2004)

§          Gebhart, C.L., Sriadibhatla, S., Vinogradov, S., Lemieux, P., Alakhov, V., and Kabanov, A.V. Design and Formulation of Polyplexes Based on Pluronic®-Polyethyleneimine Conjugates for Gene Transfer. Bioconjugate Chemistry 13(5), 937-944 (2002)

§          Gebhart, C.L., Sriadibhatla, S., Vinogradov, S and Kabanov, A.V. Pluronic-Polyethyleneimine Conjugates for Gene Delivery. Polymer Prepr (Am. Chem. Soc., Div. Polym. Chem) 42,119-120 (2000)

 

Presentations

§          Sriadibhatla, S., Yang, Z., Alakhov, V.Y and Kabanov, A.V. Pluronic Block Copolymers Effect the Gene Expression in Stably Transfected Cells. 32nd Annual meeting and Exposition of the Controlled Release Society, June’05

§          Sriadibhatla, S., Gebhart C and Kabanov, A.V.  Effect of Pluronic Block Copolymers on Gene Expression. Podium presentation at the 36th Pharmaceutics Graduate Student Research Meeting. School of pharmacy, University of Iowa, Iowa City, June’04

§          Sriadibhatla, S. Effect of Pluronic Block Copolymers on Gene Expression. PSGP seminar presented at the UNMC College of Pharmacy, April’04

§          Sriadibhatla, S., Bronich, T.K and Kabanov, A.V.  Gene Delivery using Polyelectrolyte Multilayer (PEML) Technology. Poster presentation at the 35th Pharmaceutics Graduate Student Research Meeting. School of pharmacy, University of Chicago, Illinois, June’03

§          Sriadibhatla, S., Gebhart, C.L., Vinogradov, S., and Kabanov, A.V. Pluronic® P123-Polyethyleneimine Conjugate: A Novel Non-Viral Gene Delivery System. Podium Presentation at 33rd Annual Midwest Student Biomedical Research Forum, Omaha, Feb’02

§          Gebhart, C.L., Sriadibhatla, S., Vinogradov, S., Lemieux, P., Alakhov, V., and Kabanov, A.V. The Role of Pluronic® in Dispersion Stabilization and Gene Transfer of Polyplexes based on Cationic Graft Copolymers. Poster presentation at 5th International Symposium on Polymer Therapeutics. Welsh School of Pharmacy, Cardiff University, Jan’02

§          Sriadibhatla, S., Gebhart, C.L., Vinogradov, S., and Kabanov, A.V. Intracellular trafficking and transgene expression of pDNA delivered by graft block copolymer P123PEI. Podium presentation at the 33rd Pharmaceutics Graduate Student Research Meeting. School of pharmacy, University of Wisconsin, Madison, Jan’01

Professional Memberships

§          American Association of Pharmaceutical Scientists (AAPS)

§          Controlled Release Society (CRS)

§          American Association for the Advancement of Science (AAAS)