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Joseph A. Vetro, Ph.D.

Assistant Professor
Center for Drug Delivery and Nanomedicine

and Department of Pharmaceutical Sciences
College of Pharmacy

 

Campus Address:

986025 Nebraska Medical Center
COP 3033
Omaha, NE 68198-6025

402-559-9359 (Office)
402-559-9543 (Fax)

E-mail: jvetro@unmc.edu

           

Research Activities/Interests:

Dr. Vetro's research interests are in developing novel synthetic targeted drug and gene delivery nanocarriers for the anti-angiogenesis treatment of cancer, improving development paradigms for targeted bioimaging and drug delivery nanocarriers, and developing synthetic vaccines. 

 

Honors and Awards:

2000-2001  American Heart Association Pre-Doctoral Fellowship (0010163Z)
• Intracellular Role of the Type 1 and Type 2 Methionine Aminopeptidase N-Terminal Domains
2002-2004  American Heart Association Post-Doctoral Fellowship (0225425Z)
• Generation of Novel Cationic Polymers for Gene Delivery to Vascular Endothelial Cells Using a Combinatorial Approach

 

 Recent Publications:

 

Journal Articles

(2010) Ambardekar VV, Han H-Y, Varney ML, Vinogradov SV, Singh RK, Vetro JA, “The Modification of siRNA with 3' Cholesterol to Increase Nuclease Protection and Suppression of Native mRNA by Select siRNA Polyplexes”, Biomaterials, in press
(2009) Kakiuci-Kiyota S, Vetro JA, Suzuki S, Varney ML, Han H-Y, Nascimento M, Pennington KL, Arnold LL, Singh RK, Cohen SM. Evaluation of Effects of Troglitazone on Endothelial Cells in vivo and in vitro: Differences Between Mouse and Human. Toxicol Appl Pharmacol. 237: 83-90.

(2006) Vetro JA, “Delivery, Detection, and Development in Nanomedicine”, Nanomedicine 1(4): 487-489

(2005) Braun CS, Vetro JA, Koe GS, Koe JG, Tomalia DA, Middaugh CR “Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles” J Pharm Sci  94(2): 423-436
(2005) Vetro JA, Dummitt B, Micka WS, Chang YH “Evidence of a dominant negative mutant of yeast methionine aminopeptidase type 2 in Saccharomyces cerevisiae” J Cell Biochem 94: 656-668 
(2003) Lobo BS, Vetro JA, Suich DM, Zuckermann RN, Middaugh CR “Structure/functional analysis of peptoid/lipitoid:DNA complexes” J Pharm Sci  92 (9): 1905-1918
(2002) Vetro JA and Chang YH “Yeast methionine aminopeptidase type 1 is ribosome-associated and requires its N-terminal zinc finger domain for normal function in vivo” J Cell Biochem 85: 678-688
(2002) Chen S, Vetro JA, Chang YH “The specificity in vivo of two distinct methionine aminopeptidases in Saccharomyces cerevisiae” Arch Biochem Biophys 398(1): 87-93

 

Book Chapters
(2006) Batrakova EV, Bronich TK, Vetro JA, Kabanov AV “Polymeric Micelles as Drug Carriers” in Nanoparticulates as Drug Carriers, Ed. Torchilin, V, (in press
(2004) Vetro JA, Dummitt B, Chang YH “Methionine aminopeptidase: Emerging role in angiogenesis” in Aminopeptidases in Biology and Disease, Eds. Hooper NM and Lendeckel U, Kluwer: New York, New York, pp. 17-44.